Article
Increased Variability of Genomic Transcription in Schizophrenia.
Scientific reports - 10 Dec 2015
Zhang Fuquan, Yao Shugart Yin, Yue Weihua, Cheng Zaohuo, Wang Guoqiang, Zhou Zhenhe, Jin Chunhui, Yuan Jianmin, Liu Sha, Xu Yong
Abstract excerpt
Schizophrenia (SZ) is a severe chronic mental disorder with a high heritability. Current microarray analyses typically focus on identifying differentially expressed genes or enriched pathways relevant to phenotypes. Whether there is a variability change of the genomic transcription in diseases has rarely been explored. In this study, we compared coefficient of variation (CV, the ratio of the standard deviation to...
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