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Schizophrenia Gene Expression Profile Reverted to Normal Levels by Antipsychotics

29 Jan 2015

Abstract excerpt

BACKGROUND: Despite the widespread use of antipsychotics, little is known of the molecular bases behind the action of antipsychotic drugs. A genome-wide study is needed to characterize the genes that affect the clinical response and their adverse effects. METHODS: Here we show the analysis of the blood transcriptome of 22 schizophrenia patients before and after medication with atypical antipsychotics by...

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PMID: 25522406
DOI: 10.1093/ijnp/pyu066

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