Article
Complete Response to Erlotinib and Bevacizumab in a Patient With Biphenotypic (Hepatobiliary) Primary Liver Carcinoma.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Dec 2015
Zhou Amy, Amin Manik, Fowler Kathryn J, Brunt Elizabeth M, Keller Jesse, Tan Benjamin
Abstract excerpt
Biphenotypic (hepatobiliary) primary liver carcinomas [B(H-B)PLCs] are rare tumors with features of both hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). These tumors are associated with a poor overall prognosis and treatment is not well defined. Research over the past 20 years has identified aberrations in several molecular pathways, including epidermal growth factor receptor (EGFR) and...
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