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Article

Deletion of the thymidine kinase gene induces complete attenuation of the Georgia isolate of African swine fever virus

4 Dec 2015

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26656424
DOI: 10.1016/j.virusres.2015.12.002

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Related research

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Deletion of the thymidine kinase gene induces complete attenuation of the Georgia isolate of African swine fever virusPMID 26656424Read ↗

African swine fever virus Georgia isolate harboring deletions of 9GL and MGF360/505 genes is highly attenuated in swine but does not confer protection against parental virus challengeSemantic proximity Read ↗

The L83L ORF of African swine fever virus strain Georgia encodes for a non-essential gene that interacts with the host protein IL-1βSemantic proximity Read ↗

Genomic Analysis of Highly Virulent Georgia 2007/1 Isolate of African Swine Fever VirusSemantic proximity Read ↗

Isolation and characterization of TK-deficient mutants of African swine fever virus.Semantic proximity Read ↗

The African Swine Fever Virus Thymidine Kinase Gene Is Required for Efficient Replication in Swine Macrophages and for Virulence in SwineSemantic proximity Read ↗

Differential Effect of the Deletion of African Swine Fever Virus Virulence-Associated Genes in the Induction of Attenuation of the Highly Virulent Georgia StrainSemantic proximity Read ↗

The progressive adaptation of a georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major modifications of the viral genome.Semantic proximity Read ↗

Analysis of the Complete Nucleotide Sequence of African Swine Fever VirusSemantic proximity Read ↗

Differential Effect of Deleting Members of African Swine Fever Virus Multigene Families 360 and 505 from the Genotype II Georgia 2007/1 Isolate on Virus Replication, Virulence, and Induction of Protection.Semantic proximity Read ↗

Deletion of E184L, a Putative DIVA Target from the Pandemic Strain of African Swine Fever Virus, Produces a Reduction in Virulence and Protection against Virulent ChallengeSemantic proximity Read ↗

Deletion of the H108R Gene Reduces Virulence of the Pandemic Eurasia Strain of African Swine Fever Virus with Surviving Animals Being Protected against Virulent ChallengeSemantic proximity Read ↗

Simultaneous Deletion of the9GLandUKGenes from the African Swine Fever Virus Georgia 2007 Isolate Offers Increased Safety and Protection against Homologous ChallengeSemantic proximity Read ↗

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