Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No association between the common calcium-sensing receptor polymorphism rs1801725 and irritable bowel syndrome.

BMC medical genetics - 11 Dec 2015

Romero Philipp, Schmitteckert Stefanie, Wouters Mira M, Houghton Lesley A, Czogalla Bastian, Sayuk Gregory S, Boeckxstaens Guy E, Guenther Patrick, Holland-Cunz Stefan, Niesler Beate

Abstract excerpt

BACKGROUND: The calcium-sensing receptor (CaSR) is a calcium (Ca(2+)) sensitive G protein-coupled receptor implicated in various biological processes. In particular, it regulates Ca(2+)/Mg(2+)- homeostasis and senses interstitial Ca(2+) levels and thereby controls downstream signalling cascades. Due to its expression in the gut epithelium, the enteric nervous system and smooth muscles and its key function in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Young Adult
Share to Belgium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genetic Association Studies

Share to Irritable Bowel Syndrome

Share to Receptors, Calcium-Sensing

Share to United Kingdom

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 26654249
DOI: 10.1186/s12881-015-0256-0
PMCID: PMC4676826

Genes

CASR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No association between the common calcium-sensing receptor polymorphism rs1801725 and irritable bowel syndrome.PMID 26654249Read ↗

Genetic variation in calcium-sensing receptor and risk for colon cancer.Semantic proximity Read ↗

Is there a link between the calcium sensing receptor and Hirschsprung's disease? A mutational analysis.Semantic proximity Read ↗

Association between CASR polymorphisms, calcium intake, and colorectal cancer risk.Semantic proximity Read ↗

CASR rs1801725 polymorphism is associated with the risk and prognosis of colorectal cancer: A case-control study.Semantic proximity Read ↗

The Role of Ion Channels in Functional Gastrointestinal Disorders (FGID): Evidence of Channelopathies and Potential Avenues for Future Research and Therapeutic TargetsSemantic proximity Read ↗

Calcium-sensing receptor gene polymorphisms in patients with calcium urolithiasis: a systematic review.Semantic proximity Read ↗

Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene.Semantic proximity Read ↗

Parathyroid hormone gene rs6256 and calcium sensing receptor gene rs1801725 variants are not associated with susceptibility to colorectal cancer in Iran.Semantic proximity Read ↗

Common calcium-sensing receptor (CASR) gene variants do not modify risk for chronic pancreatitis in a Hungarian cohort.Semantic proximity Read ↗

A986S polymorphism of the calcium-sensing receptor and circulating calcium concentrations.Semantic proximity Read ↗

SCGN deficiency results in colitis susceptibility.Semantic proximity Read ↗

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.