Article
Helicobacter pylori Resists the Antimicrobial Activity of Calprotectin via Lipid A Modification and Associated Biofilm Formation.
mBio - 8 Dec 2015
Gaddy Jennifer A, Radin Jana N, Cullen Thomas W, Chazin Walter J, Skaar Eric P, Trent M Stephen, Algood Holly M S
Abstract excerpt
UNLABELLED: Helicobacter pylori is one of several pathogens that persist within the host despite a robust immune response. H. pylori elicits a proinflammatory response from host epithelia, resulting in the recruitment of immune cells which manifests as gastritis. Relatively little is known about how H. pylori survives antimicrobials, including calprotectin (CP), which is present during the inflammatory response....
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