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Characterization of a second open reading frame in genome segment 10 of bluetongue virus

19 Aug 2015

Abstract excerpt

Viruses have often evolved overlapping reading frames in order to maximize their coding capacity. Until recently, the segmented dsRNA genome of viruses of the Orbivirus genus was thought to be monocistronic, but the identification of the bluetongue virus (BTV) NS4 protein changed this assumption. A small ORF in segment 10, overlapping the NS3 ORF in the +1 position, is maintained in more than 300 strains of the...

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Identifiers

PMID: 26290332
DOI: 10.1099/jgv.0.000267

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