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Article

Piperine impairs the migration and T cell-activating function of dendritic cells.

Toxicology letters - 3 Feb 2016

Rodgers Gemma, Doucette Carolyn D, Soutar David A, Liwski Robert S, Hoskin David W

Abstract excerpt

Piperine, a major alkaloid found in the fruits of black and long pepper plants, has anti-inflammatory properties; however, piperine's effect on dendritic cell (DC) migration and T cell-activating function has not been investigated. Bone marrow-derived mouse DCs that were matured in the presence of 100 μM piperine showed reduced in vitro migration in response to CCL21, as well as reduced in vivo migration to lymph...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26640239
DOI: 10.1016/j.toxlet.2015.11.025

Genes

CCL21
CCR5
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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