Article
Genetic Polymorphism of CHRM2 in COPD: Clinical Significance and Therapeutic Implications.
Journal of cellular physiology - 1 Aug 2016
Cherubini Emanuela, Esposito Maria Cristina, Scozzi Davide, Terzo Fabrizio, Osman Giorgia Amira, Mariotta Salvatore, Mancini Rita, Bruno Pierdonato, Ricci Alberto
Abstract excerpt
Chronic Obstructive Pulmonary Disease (COPD) is a common preventable and treatable disease, characterized by persistent airflow limitation not fully reversible. However, a number of patients with COPD respond to bronchodilator agents. Some studies have shown polymorphisms in the b2-adrenergic (ADRb2) and muscarinic M2 and M3 receptors (CHRM) that may participate in the modulation of the receptor responses. This...
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