Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NFAT4-dependent miR-324-5p regulates mitochondrial morphology and cardiomyocyte cell death by targeting Mtfr1

3 Dec 2015

Abstract excerpt

Emerging evidence suggest that the abnormal mitochondrial fission participates in pathogenesis of cardiac diseases, including myocardial infarction and heart failure. However, the molecular components regulating mitochondrial network in heart remain largely unidentified. Here we report that NFAT4, miR-324-5p and mitochondrial fission regulator 1 (Mtfr1) function in one signaling axis that regulates mitochondrial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Ischemia and Reperfusion
Share to MicroRNA in disease regulation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26633713
DOI: 10.1038/cddis.2015.348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NFAT4-dependent miR-324-5p regulates mitochondrial morphology and cardiomyocyte cell death by targeting Mtfr1PMID 26633713Read ↗

Role of Mitochondrial Dynamics in Heart DiseasesSemantic proximity Read ↗

Nuclear receptor subfamily 4 group A member 1 promotes myocardial ischemia/reperfusion injury through inducing mitochondrial fission factor-mediated mitochondrial fragmentation and inhibiting FUN14 domain containing 1-depedent mitophagySemantic proximity Read ↗

New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology.Semantic proximity Read ↗

Mitochondrial fission process 1 (MTFP1) controls bioenergetic efficiency and prevents inflammatory cardiomyopathy and heart failure in miceSemantic proximity Read ↗

NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2α.Semantic proximity Read ↗

METTL3 boosts mitochondrial fission and induces cardiac fibrosis by enhancing LncRNA GAS5 methylationSemantic proximity Read ↗

Emerging functions of mammalian mitochondrial fusion and fission.Semantic proximity Read ↗

Dysregulation of mitochondrial fusion and fission: an emerging concept in neurodegeneration.Semantic proximity Read ↗

The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.Semantic proximity Read ↗

Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence.Semantic proximity Read ↗

Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured FibroblastsSemantic proximity Read ↗

Disruption of cTnT-Mediated Sarcomere–Mitochondrial Communication Results in Dilated CardiomyopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.