Article
The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.
Molecular biology of the cell - 1 Jun 2008
Gandre-Babbe Shilpa, van der Bliek Alexander M
Abstract excerpt
Few components of the mitochondrial fission machinery are known, even though mitochondrial fission is a complex process of vital importance for cell growth and survival. Here, we describe a novel protein that controls mitochondrial fission. This protein was identified in a small interfering RNA (siRNA) screen using Drosophila cells. The human homologue of this protein was named Mitochondrial fission factor (Mff)....
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