Article
Characterization and Mutational Analysis of a Two-Polypeptide Bacteriocin Produced by Citrus Iyo-Derived Lactobacillus brevis 174A.
Biological & pharmaceutical bulletin - 1 Jan 2015
Noda Masafumi, Miyauchi Rumi, Danshiitsoodol Narandalai, Higashikawa Fumiko, Kumagai Takanori, Matoba Yasuyuki, Sugiyama Masanori
Abstract excerpt
In the present study, we isolated a lactic acid bacterium (LAB) from a citrus iyo fruit and identified it as Lactobacillus brevis. This plant-derived LAB strain, designated 174A, produces bacteriocin consisting of two polypeptides designated brevicin 174A-β and 174A-γ. Although each polypeptide itself displays antibacterial activity, the ability is enhanced 100 fold by mixing both polypeptides at a 1 : 1 ratio....
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