Article
Identification of the lantibiotic nisin Q, a new natural nisin variant produced by Lactococcus lactis 61-14 isolated from a river in Japan.
Bioscience, biotechnology, and biochemistry - 1 Jul 2003
Zendo Takeshi, Fukao Masanori, Ueda Kyoko, Higuchi Tomoko, Nakayama Jiro, Sonomoto Kenji
Abstract excerpt
Lactococcus lactis 61-14 isolated from river water produced a bacteriocin active against a wide range of Gram-positive bacteria. N-terminal amino acid sequencing, mass spectral analysis of the purified bacteriocin, and genetic analysis using nisin-specific primers showed that the bacteriocin was a new natural nisin variant, termed nisin Q. Nisin Q and nisin A differ in four amino acids in the mature peptide and...
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