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Article

Visualization of NO3⁻/NO2⁻ Dynamics in Living Cells by Fluorescence Resonance Energy Transfer (FRET) Imaging Employing a Rhizobial Two-component Regulatory System.

The Journal of biological chemistry - 29 Jan 2016

Hidaka Masafumi, Gotoh Aina, Shimizu Taiki, Minamisawa Kiwamu, Imamura Hiromi, Uchida Takafumi

Abstract excerpt

Nitrate (NO3(-)) and nitrite (NO2(-)) are the physiological sources of nitric oxide (NO), a key biological messenger molecule. NO3(-)/NO2(-) exerts a beneficial impact on NO homeostasis and its related cardiovascular functions. To visualize the physiological dynamics of NO3(-)/NO2(-) for assessing the precise roles of these anions, we developed a genetically encoded intermolecular fluorescence resonance energy...

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Identifiers

PMID: 26631727
DOI: 10.1074/jbc.M115.687632
PMCID: PMC4732209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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