Article
Gene expression variance in hippocampal tissue of temporal lobe epilepsy patients corresponds to differential memory performance.
Neurobiology of disease - 1 Feb 2016
Bungenberg Julia, Surano Natascha, Grote Alexander, Surges Rainer, Pernhorst Katharina, Hofmann Andrea, Schoch Susanne, Helmstaedter Christoph, Becker Albert J
Abstract excerpt
Temporal lobe epilepsy (TLE) is a severe brain disorder affecting particularly young adults. TLE is frequently associated with memory deterioration and neuronal damage of the hippocampal formation. It thereby reveals striking parallels to neurodegenerative disorders including Alzheimer's disease (AD). TLE patients differ with respect to their cognitive performance, but currently little is known about relevant...
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