Article
Powerful Tests for Multi-Marker Association Analysis Using Ensemble Learning.
PloS one - 1 Jan 2015
Padhukasahasram Badri, Reddy Chandan K, Levin Albert M, Burchard Esteban G, Williams L Keoki
Abstract excerpt
Multi-marker approaches have received a lot of attention recently in genome wide association studies and can enhance power to detect new associations under certain conditions. Gene-, gene-set- and pathway-based association tests are increasingly being viewed as useful supplements to the more widely used single marker association analysis which have successfully uncovered numerous disease variants. A major...
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