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Article

Establishment of stable multiple myeloma cell line with overexpressed PDCD5 and its proapoptosis mechanism.

International journal of clinical and experimental pathology - 1 Jan 2015

Feng Wenchang, Fu Yunfeng, Zhang Yanan, Lv Ben, Li Xin, Zhang Fan, Gui Rong, Liu Jing

Abstract excerpt

OBJECTIVE: The transfected multiple myeloma cell line showing a stable doxycycline (DOX)-induced expression of PDCD5 was established. PDCD5 overexpression in the transfected cell line was analyzed for its effect on the dexamethasone (DXM)-induced apoptosis along with a discussion on the mechanism. METHODS: (1) Lentiviral plasmid was used for the transfection of PDCD5 gene into the multiple myeloma cells. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26617773
PMCID: PMC4637588

Genes

PDCD5
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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