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Article

The ultra-slow NAT2*6A haplotype is associated with reduced higher cognitive functions in an elderly study group.

Archives of toxicology - 1 Dec 2015

Selinski Silvia, Getzmann Stephan, Gajewski Patrick D, Blaszkewicz Meinolf, Hengstler Jan G, Falkenstein Michael, Golka Klaus

Abstract excerpt

N-Acetyltransferase 2 (NAT2) genotype is associated with age-related declines in basic sensory hearing functions. However, the possible modulatory role of NAT2 for higher cognitive functions has not yet been studied. We tested auditory goal-directed behavior and attentional control in 120 NAT2 genotyped subjects (63-88 years), using an auditory distraction paradigm in which participants responded to the duration...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26615528
DOI: 10.1007/s00204-015-1635-1

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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