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Article

Modelling metabolic evolution on phenotypic fitness landscapes: a case study on C4 photosynthesis.

Biochemical Society transactions - 1 Dec 2015

Heckmann David

Abstract excerpt

How did the complex metabolic systems we observe today evolve through adaptive evolution? The fitness landscape is the theoretical framework to answer this question. Since experimental data on natural fitness landscapes is scarce, computational models are a valuable tool to predict landscape topologies and evolutionary trajectories. Careful assumptions about the genetic and phenotypic features of the system under...

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PMID: 26614656
DOI: 10.1042/BST20150148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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