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Article

Predicting C4 photosynthesis evolution: modular, individually adaptive steps on a Mount Fuji fitness landscape.

Cell - 20 Jun 2013

Heckmann David, Schulze Stefanie, Denton Alisandra, Gowik Udo, Westhoff Peter, Weber Andreas P M, Lercher Martin J

Abstract excerpt

An ultimate goal of evolutionary biology is the prediction and experimental verification of adaptive trajectories on macroevolutionary timescales. This aim has rarely been achieved for complex biological systems, as models usually lack clear correlates of organismal fitness. Here, we simulate the fitness landscape connecting two carbon fixation systems: C3 photosynthesis, used by most plant species, and the C4...

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Source

Identifiers

PMID: 23791184
DOI: 10.1016/j.cell.2013.04.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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