Article
Impact of oncogenic BRAF mutations and p16 expression on the growth rate of early melanomas and naevi in vivo.
The British journal of dermatology - 1 Feb 2016
Tschandl P, Berghoff A S, Preusser M, Pammer J, Pehamberger H, Kittler H
Abstract excerpt
BACKGROUND: It is important to know what drives and arrests melanocytic growth in vivo but observations linking oncogenic mutations to growth rates of melanocytic neoplasms in vivo are sparse. OBJECTIVES: To clarify the relationship between BRAF(V) (600E) mutations and p16 expression and the growth rate of melanocytic neoplasms in vivo. METHODS: We measured the growth rate of 54 melanocytic lesions (26 melanomas,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
