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Article

Polymorphisms of the eNOS gene are associated with disease activity in rheumatoid arthritis.

Rheumatology international - 1 Apr 2016

Bunjevacki Vera, Maksimovic Nela, Jekic Biljana, Milic Vera, Lukovic Ljiljana, Novakovic Ivana, Damjanov Nemanja, Radunovic Goran, Damnjanovic Tatjana

Abstract excerpt

Nitric oxide (NO) is a mediator in autoimmune responses and thus involved in the pathogenesis of a variety of rheumatic diseases. Genetic factors that influence the expression of the enzyme endothelial nitric oxide synthase (eNOS) that catalyzes NO synthesis are important for the control of NO level and consequently its activity. We have analyzed three functionally relevant polymorphisms of eNOS gene: T-786C,...

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PMID: 26612436
DOI: 10.1007/s00296-015-3401-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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