Article
Endothelial nitric oxide synthase T-786C polymorphism in rheumatoid arthritis: association with extraarticular manifestations.
Clinical rheumatology - 1 Feb 2009
Brenol Claiton Viegas, Chies José Artur Bogo, Brenol João Carlos Tavares, Monticielo Odirlei André, Franciscatto Paulo, Birriel Felipe, Neves Andrei Gibbon, Xavier Ricardo Machado
Abstract excerpt
Several genetic factors were implicated in the pathogenesis of rheumatoid arthritis (RA). A case-control study was carried out to verify the associations of T-786C polymorphism in the promoter region of the endothelial nitric oxide synthase (eNOS) gene with RA. One hundred and five consecutive RA patients and 100 healthy controls were genotyped. The distribution of the T-786C genotype and alleles did not differ...
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