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Article

Identification of polymorphic variants associated with erlotinib-related skin toxicity in advanced non-small cell lung cancer patients by DMET microarray analysis.

Cancer chemotherapy and pharmacology - 1 Jan 2016

Arbitrio Mariamena, Di Martino Maria Teresa, Barbieri Vito, Agapito Giuseppe, Guzzi Pietro Hiram, Botta Cirino, Iuliano Eleonora, Scionti Francesca, Altomare Emanuela, Codispoti Stefania, Conforti Serafino, Cannataro Mario, Tassone Pierfrancesco, Tagliaferri Pierosandro

Abstract excerpt

PURPOSE: Erlotinib is a targeted agent commonly used in advanced non-small cell lung cancer (aNSCLC). However, drug-related skin toxicity often may affect the quality of life of cancer patients and lead to treatment discontinuation. Genetic polymorphisms in drug transporters and metabolizing enzy...

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Source

Identifiers

PMID: 26607259
DOI: 10.1007/s00280-015-2916-3

Genes

ADH6
CHST1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-26607259-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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