Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes.

doi:10.1038/s41598-022-22914-6

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes.

Scientific reports - 26 Oct 2022

Ohnami Sumiko, Naruoka Akane, Isaka Mitsuhiro, Mizuguchi Maki, Nakatani Sou, Kamada Fukumi, Shimoda Yuji, Sakai Ai, Ohshima Keiichi, Hatakeyama Keiichi, Maruyama Kouji, Ohde Yasuhisa, Kenmotsu Hirotsugu, Takahashi Toshiaki, Akiyama Yasuto, Nagashima Takeshi, Urakami Kenichi, Ohnami Shumpei, Yamaguchi Ken

Abstract excerpt

The differences in genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma remain unclear. We developed a customized, targeted gene sequencing panel for efficient and sensitive identification of germline variants, including whole-gene deletion types for cancer-related drug-metabolizing enzyme genes in lung adenocarcinoma and squamous cell carcinoma. The minor allele frequencies of the variants,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adenocarcinoma of Lung

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Carcinoma, Squamous Cell

Share to Case-Control Studies

Share to Japan

Share to Lung Neoplasms

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 36289279
DOI: 10.1038/s41598-022-22914-6
PMCID: PMC9606290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes.PMID 36289279Read ↗

CYP2A6 deletion polymorphism is associated with decreased susceptibility of lung cancer in Asian smokers: a meta-analysis.Semantic proximity Read ↗

Association of CYP2A6*4 with susceptibility of lung cancer: a meta-analysis.Semantic proximity Read ↗

Dual-specificity phosphatase 6 genetic variants associated with risk of lung squamous cell carcinoma in Han Chinese.Semantic proximity Read ↗

A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.Semantic proximity Read ↗

CYP2A6 genetic polymorphism is associated with decreased susceptibility to squamous cell lung cancer in Japanese smokers.Semantic proximity Read ↗

Identification of genome variations in patients with lung adenocarcinoma using whole genome re‑sequencing.Semantic proximity Read ↗

Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population.Semantic proximity Read ↗

Association between cancer risk and drug-metabolizing enzyme gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) polymorphisms in cases of lung cancer in Japan.Semantic proximity Read ↗

A comprehensive meta-analysis and a case-control study give insights into genetic susceptibility of lung cancer and subgroups.Semantic proximity Read ↗

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.Semantic proximity Read ↗

Prognostic Impact of CDKN2A Mutations Associated With Smoking and Drinking History in Japanese Digestive Cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.