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Article

Identification of genetic variations associated with drug resistance in non-small cell lung cancer patients undergoing systemic treatment.

Briefings in bioinformatics - 5 Nov 2021

Luo Ruihan, Ge Chuang, Xiao Xiao, Song Jing, Miao Shiqi, Tang Yongyao, Lai Jiayi, Nian Weiqi, Song Fangzhou, Ran Longke

Abstract excerpt

Non-small cell lung cancer (NSCLC) is characterized by relatively rapid response to systemic treatments yet inevitable resistance and predisposed to distant metastasis. We thus aimed at performing sequencing analysis to determine genomic events and underlying mechanisms concerning drug resistance in NSCLC. We performed targeted sequencing of 40 medication-relevant genes on plasma samples from 98 NSCLC patients...

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Share to Antineoplastic Combined Chemotherapy Protocols
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34013324
DOI: 10.1093/bib/bbab187
PMCID: PMC8574960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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