Article
Genome-wide association study identifies common and low-frequency variants at the AMH gene locus that strongly predict serum AMH levels in males.
Human molecular genetics - 15 Jan 2016
Perry John R B, McMahon George, Day Felix R, Ring Susan M, Nelson Scott M, Lawlor Debbie A
Abstract excerpt
Anti-Müllerian hormone (AMH) is an essential messenger of sexual differentiation in the foetus and is an emerging biomarker of postnatal reproductive function in females. Due to a paucity of adequately sized studies, the genetic determinants of circulating AMH levels are poorly characterized. In samples from 2815 adolescents aged 15 from the ALSPAC study, we performed the first genome-wide association study of...
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