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AMH and AMHR2 Involvement in Congenital Disorders of Sex Development

31 Aug 2021

Abstract excerpt

Anti-müllerian hormone (AMH) is 1 of the 2 testicular hormones involved in male development of the genitalia during fetal life. When the testes differentiate, AMH is secreted by Sertoli cells and binds to its specific receptor type II (AMHR2) on the müllerian ducts, inducing their regression. In the female fetus, the lack of AMH allows the müllerian ducts to form the fallopian tubes, the uterus, and the upper...

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PMID: 34515230
DOI: 10.1159/000518273

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