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Article

The prognostic values of CYP2B6 genetic polymorphisms and metastatic sites for advanced breast cancer patients treated with docetaxel and thiotepa.

Scientific reports - 25 Nov 2015

Song Qingkun, Zhou Xinna, Yu Jing, Dong Ningning, Wang Xiaoli, Yang Huabing, Ren Jun, Lyerly H Kim

Abstract excerpt

This study investigated interactive effects of CYP2B6 genotypes and liver metastasis on the prognosis of metastatic breast cancer patients who received combined chemotherapy of docetaxel and thiotepa. Totally 153 patients were retrospectively genotyped rs8192719 (c.1294 + 53C > T) and rs2279343 (c.785A > G). Kaplan-Meier method and Cox Proportional Hazard Regression model were used to estimate the survival....

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Identifiers

PMID: 26602960
DOI: 10.1038/srep16775
PMCID: PMC4658481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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