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Article

Influence of iron regulation on the metabolome of Cryptococcus neoformans.

PloS one - 1 Jan 2012

Choi Jung Nam, Kim Jeongmi, Kim Jiyoung, Jung Won Hee, Lee Choong Hwan

Abstract excerpt

Iron is an essential nutrient for virtually all organisms and acts as a cofactor for many key enzymes of major metabolic pathways. Furthermore, iron plays a critical role in pathogen-host interactions. In this study, we analyzed metabolomic changes associated with iron availability and the iron regulatory protein Cir1 in a human fungal pathogen Cryptococcus neoformans. Our metabolite analysis revealed that Cir1...

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Identifiers

PMID: 22911836
DOI: 10.1371/journal.pone.0041654
PMCID: PMC3402442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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