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Article

Paradoxical Relationship Between Body Mass Index and Thyroid Hormone Levels: A Study Using Mendelian Randomization.

The Journal of clinical endocrinology and metabolism - 1 Feb 2016

Taylor Peter N, Richmond Rebecca, Davies Neil, Sayers Adrian, Stevenson Kirsty, Woltersdorf Wolfram, Taylor Andrew, Groom Alix, Northstone Kate, Ring Susan, Okosieme Onyebuchi, Rees Aled, Nitsch Dorothea, Williams Graham R, Smith George Davey, Gregory John W, Timpson Nicholas J, Tobias Jonathan H, Dayan Colin M

Abstract excerpt

CONTEXT: Free T3 (FT3) has been positively associated with body mass index (BMI) in cross-sectional studies in healthy individuals. This is difficult to reconcile with clinical findings in pathological thyroid dysfunction. OBJECTIVE: We aimed to investigate whether childhood adiposity influences FT3 levels. DESIGN: Mendelian randomization using genetic variants robustly associated with BMI. SETTING: Avon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26595101
DOI: 10.1210/jc.2015-3505
PMCID: PMC4880123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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