Article
Association of Epidemiologic Factors and Genetic Variants Influencing Hypothalamic-Pituitary-Adrenocortical Axis Function With Postconcussive Symptoms After Minor Motor Vehicle Collision.
Psychosomatic medicine - 1 Jan 2016
Auvergne Lauriane, Bortsov Andrey V, Ulirsch Jacob C, Peak David A, Jones Jeffrey S, Swor Robert A, Domeier Robert M, Lee David C, Rathlev Niels K, Hendry Phyllis L, McLean Samuel A
Abstract excerpt
OBJECTIVES: To determine the influence of epidemiologic factors and the influence of genetic variants affecting FKBP5, a protein known to modulate hypothalamic-pituitary-adrenocortical axis function, on the severity of somatic symptoms commonly termed "postconcussive" 6 and 12 months after motor vehicle collision (MVC). METHODS: European Americans 18 to 65 years of age who presented to one of eight emergency...
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