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Article

μ-Opioid Receptor Gene A118 G Variants and Persistent Pain Symptoms Among Men and Women Experiencing Motor Vehicle Collision.

The journal of pain - 1 Jul 2015

Linnstaedt Sarah D, Hu JunMei, Bortsov Andrey V, Soward April C, Swor Robert, Jones Jeffrey, Lee David, Peak David, Domeier Robert, Rathlev Niels, Hendry Phyllis, McLean Samuel A

Abstract excerpt

UNLABELLED: The μ-opioid receptor 1 (OPRM1) binds endogenous opioids. Increasing evidence suggests that endogenous OPRM1 agonists released at the time of trauma may contribute to the development of posttraumatic musculoskeletal pain (MSP). In this prospective observational study, we evaluated the hypothesis that individuals with an AG or GG genotype at the OPRM1 A118 G allele, which results in a reduced response...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25842347
DOI: 10.1016/j.jpain.2015.03.011
PMCID: PMC4486521

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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