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Article

Embryonic oxidative stress results in reproductive impairment for adult zebrafish.

Redox biology - 1 Dec 2015

Newman Trent A C, Carleton Catherine R, Leeke Bryony, Hampton Mark B, Horsfield Julia A

Abstract excerpt

Exposure to environmental stressors during embryo development can have long-term effects on the adult organism. This study used the thioredoxin reductase inhibitor auranofin to investigate the consequences of oxidative stress during zebrafish development. Auranofin at low doses triggered upregulation of the antioxidant genes gstp1 and prdx1. As the dose was increased, acute developmental abnormalities, including...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26584358
DOI: 10.1016/j.redox.2015.10.010
PMCID: PMC4656920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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