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Article

Remission of congenital hyperinsulinism following conservative treatment: an exploratory study in patients with KATP channel mutations.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Mar 2016

Lachmann Mark J, Salgin Burak, Kummer Sebastian, Welters Alena, Döing Carsten, Zenker Martin, Wieland Ilse, Mayatepek Ertan, Meissner Thomas

Abstract excerpt

BACKGROUND: During conservative treatment, congenital hyperinsulinism (CHI) can resolve spontaneously. This study describes the hormonal and metabolic profiles in three patients with ABCC8/KCNJ11 mutations in clinical remission. METHODS: An age-adapted fasting and oral glucose tolerance test (OGTT) were performed. RESULTS: All patients (aged 6-9 years) tolerated age-adapted fasting durations (20, respectively 24...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26581065
DOI: 10.1515/jpem-2015-0192

Genes

ABCC8
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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