Article
Increased plasma incretin concentrations identifies a subset of patients with persistent congenital hyperinsulinism without KATP channel gene defects.
The Journal of pediatrics - 1 Jan 2015
Shi Yanqin, Avatapalle Hima B, Skae Mars S, Padidela Raja, Newbould Melanie, Rigby Lindsey, Flanagan Sarah E, Ellard Sian, Rahier Jacques, Clayton Peter E, Dunne Mark J, Banerjee Indraneel, Cosgrove Karen E
Abstract excerpt
Congenital hyperinsulinism causes profound hypoglycemia, which may persist or resolve spontaneously. Among 13 children with congenital hyperinsulinism, elevated incretin hormone concentrations were detected in 2 with atypical, persistent disease. We suggest that incretin biomarkers may identify t...
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