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Article

BRCA1, BRCA2 and PALB2 mutations and CHEK2 c.1100delC in different South African ethnic groups diagnosed with premenopausal and/or triple negative breast cancer.

BMC cancer - 17 Nov 2015

Francies F Z, Wainstein T, De Leeneer K, Cairns A, Murdoch M, Nietz S, Cubasch H, Poppe B, Van Maerken T, Crombez B, Coene I, Kerr R, Slabbert J P, Vral A, Krause A, Baeyens A, Claes K B M

Abstract excerpt

BACKGROUND: Current knowledge of the aetiology of hereditary breast cancer in the four main South African population groups (black, coloured, Indian and white) is limited. Risk assessments in the black, coloured and Indian population groups are challenging because of restricted information regarding the underlying genetic contributions to inherited breast cancer in these populations. We focused this study on...

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Identifiers

PMID: 26577449
DOI: 10.1186/s12885-015-1913-6
PMCID: PMC4647511

Genes

BRCA2
BRCA1
PALB2
CHEK2

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