Article
Vitamin D, leptin and impact on immune response to seasonal influenza A/H1N1 vaccine in older persons.
Human vaccines & immunotherapeutics - 3 Mar 2016
Sadarangani Sapna P, Ovsyannikova Inna G, Goergen Krista, Grill Diane E, Poland Gregory A
Abstract excerpt
BACKGROUND: Influenza-related complications are highest in the elderly. Vaccine efficacy is lower due to immunosenescence. Vitamin D's immunomodulatory role was studied in the context of vaccine response. METHODS: We evaluated the effect of baseline 25-(OH) D on vaccine-induced immunological response in a cohort of 159 healthy subjects ages 50-74 in Rochester, MN, who received one dose of seasonal trivalent...
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