Article
High sensitivity detection of HIV-1 using two genomic targets compared with single target PCR.
Journal of medical virology - 1 Jun 2016
Shah Krishna, Ragupathy Viswanath, Saga Anusha, Hewlett Indira
Abstract excerpt
The genetic diversity of Human Immunodeficiency Virus type-1(HIV-1) has been shown to affect the performance of Nucleic Acid Testing (NAT) of Human Immunodeficiency Virus type-1. Although, majority NAT assays were designed to detect the conserved regions of HIV-1 mutations at the primer or probe binding regions may lead to false negatives. In this study, we evaluated the feasibility of detecting two genomic...
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