Article
Invasion Patterns of Metastatic Extrauterine High-grade Serous Carcinoma With BRCA Germline Mutation and Correlation With Clinical Outcomes.
The American journal of surgical pathology - 1 Mar 2016
Hussein Yaser R, Ducie Jennifer A, Arnold Angela G, Kauff Noah D, Vargas-Alvarez Hebert A, Sala Evis, Levine Douglas A, Soslow Robert A
Abstract excerpt
Characteristic histopathologic features have been described in high-grade serous carcinoma associated with BRCA abnormalities (HGSC-BRCA), which are known to have relatively favorable clinical outcomes. The aim of this study was to evaluate the clinical significance of invasion patterns in metastatic HGSC-BRCA cases. Of the 37 cases of advanced-stage HGSC with known BRCA1 or BRCA2 germline mutation retrieved from...
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