Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of Pathogenic Genes in Chinese sporadic Hypertrophic Cardiomyopathy Patients by Whole Exome Sequencing.

Scientific reports - 17 Nov 2015

Xu Jing, Li Zhongshan, Ren Xianguo, Dong Ming, Li Jinxin, Shi Xingjuan, Zhang Yu, Xie Wei, Sun Zhongsheng, Liu Xiangdong, Dai Qiming

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is a cardiovascular disease with high heterogeneity. Limited knowledge concerning the genetic background of nearly 40% HCM cases indicates there is a clear need for further investigation to explore the genetic pathogenesis of the disease. In this study, we undertook a whole exome sequencing (WES) approach to identify novel candidate genes and mutations associated with HCM. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy, Hypertrophic
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to High-Throughput Nucleotide Sequencing

Share to INDEL Mutation

Share to Protein Interaction Maps

Share to Sarcomeres

Source

Open in PubMed Open full text

Identifiers

PMID: 26573135
DOI: 10.1038/srep16609
PMCID: PMC4647833

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of Pathogenic Genes in Chinese sporadic Hypertrophic Cardiomyopathy Patients by Whole Exome Sequencing.PMID 26573135Read ↗

Genetic variants in Chinese patients with sporadic dilated cardiomyopathy: a cross-sectional studySemantic proximity Read ↗

Whole-exome sequencing reveals a likely pathogenic LMNA variant causing hypertrophic cardiomyopathy.Semantic proximity Read ↗

Exome sequencing identifies a FHOD3 p.S527del mutation in a Chinese family with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Targeted exome analysis of Russian patients with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Genetic analysis using targeted next-generation sequencing of sporadic Chinese patients with idiopathic dilated cardiomyopathy.Semantic proximity Read ↗

Molecular analysis of inherited cardiomyopathy using next generation semiconductor sequencing technologies.Semantic proximity Read ↗

Whole exome sequence reveals genetic profiles of primary cardiomyopathy and genotype-phenotype association in Chinese populationSemantic proximity Read ↗

Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Whole-exome sequencing reveals doubly novel heterozygous Myosin Binding Protein C and Titin mutations in a Chinese patient with severe dilated cardiomyopathy.Semantic proximity Read ↗

Targeted Next-Generation Sequencing Reveals Hot Spots and Doubly Heterozygous Mutations in Chinese Patients with Familial Cardiomyopathy.Semantic proximity Read ↗

Next-generation sequencing identifies pathogenic and modifier mutations in a consanguineous Chinese family with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Genetic characterization of dilated cardiomyopathy patients undergoing heart transplantation in the Chinese population by whole-exome sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.