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Article

Insights into the molecular evolution of Dengue virus type 4 in Puerto Rico over two decades of emergence.

Virus research - 2 Feb 2016

Martin Estelle, Chirivella Maritza, Co Juliene K G, Santiago Gilberto A, Gubler Duane J, Muñoz-Jordán Jorge L, Bennett Shannon N

Abstract excerpt

Dengue has emerged globally as a major human health problem since the 1950s and is now the most important arboviral disease of humans, infecting nearly 400 million people annually. While some cases are asymptomatic, others can develop a febrile illness (dengue fever) or even progress to severe and fatal dengue. Dengue is caused by any of 4 closely related but distinct viruses, known as Dengue virus serotype 1 to...

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Identifiers

PMID: 26569594
DOI: 10.1016/j.virusres.2015.11.009
PMCID: PMC4767545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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