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Tissue-specific transcriptomics and proteomics of a filarial nematode and its Wolbachia endosymbiont

11 Nov 2015

Abstract excerpt

BACKGROUND: Filarial nematodes cause debilitating human diseases. While treatable, recent evidence suggests drug resistance is developing, necessitating the development of novel targets and new treatment options. Although transcriptomic and proteomic studies around the nematode life cycle have greatly enhanced our knowledge, whole organism approaches have not provided spatial resolution of gene expression, which...

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PMID: 26559510
DOI: 10.1186/s12864-015-2083-2

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