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Rapid High-pH Reverse Phase StageTip for Sensitive Small-Scale Membrane Proteomic Profiling.

Analytical chemistry - 15 Dec 2015

Dimayacyac-Esleta Baby Rorielyn T, Tsai Chia-Feng, Kitata Reta Birhanu, Lin Pei-Yi, Choong Wai-Kok, Lin Tai-Du, Wang Yi-Ting, Weng Shao-Hsing, Yang Pan-Chyr, Arco Susan D, Sung Ting-Yi, Chen Yu-Ju

Abstract excerpt

Membrane proteins are crucial targets for cancer biomarker discovery and drug development. However, in addition to the inherent challenges of hydrophobicity and low abundance, complete membrane proteome coverage of clinical specimen is usually hindered by the requirement of large amount of starting materials. Toward comprehensive membrane proteomic profiling for small amounts of samples (10 μg), we developed...

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PMID: 26554430
DOI: 10.1021/acs.analchem.5b03639

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EGFR
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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