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Article

GLI1 expression is an important prognostic factor that contributes to the poor prognosis of rhabdomyosarcoma.

1 Mar 2016

Abstract excerpt

The GLI1 and MDM2 genes are amplified or exhibit copy number gains in rhabdomyosarcoma (RMS). Here, we used immunohistochemistry to determine the relationships between GLI1 and MDM2 protein expression and several clinicopathological variables of RMS. GLI1 and MDM2-positivity rates were 61.36% and 13.64%, respectively. GLI1 expression correlated with presence of the PAX3-FOXO1 fusion gene (P=0.040) and lymph node...

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PMID: 26544916
DOI: 10.14670/hh-11-682

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