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Maternal high-fat hypercaloric diet during pregnancy results in persistent metabolic and respiratory abnormalities in offspring

5 Nov 2015

Abstract excerpt

BACKGROUND: We have shown in a previous population-based study significant correlation between childhood asthma and early abnormalities of lipid and glucose metabolism. This study's specific aim was to determine whether maternal nutrition in pregnancy affects postnatal metabolic and respiratory outcomes in the offspring. METHODS: On gestation day 1, dams were switched from standard chow to either high-fat...

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PMID: 26539661
DOI: 10.1038/pr.2015.226

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