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Genetic Risk Factors in Idiopathic and Non-Idiopathic Interstitial Lung Disease: Similarities and Differences.

Medicina (Kaunas, Lithuania) - 29 Nov 2024

Cerri Stefania, Manzini Elisa, Nori Ottavia, Pacchetti Lucia, Rossi Laura, Turchiano Maria Giulia, Samarelli Anna Valeria, Raineri Giulia, Andrisani Dario, Gozzi Filippo, Beghè Bianca, Clini Enrico, Tonelli Roberto

Abstract excerpt

Recent advances in genetics and epigenetics have provided critical insights into the pathogenesis of both idiopathic and non-idiopathic interstitial lung diseases (ILDs). Mutations in telomere-related genes and surfactant proteins have been linked to familial pulmonary fibrosis, while variants in MUC5B and TOLLIP increase the risk of ILD, including idiopathic pulmonary fibrosis and rheumatoid arthritis-associated...

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DNA Methylation
Epigenesis, Genetic
Genetic Predisposition to Disease
Idiopathic Pulmonary Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lung Diseases, Interstitial

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PMID: 39768847
DOI: 10.3390/medicina60121967

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