Article
Associations of transcription factor 7-Like 2 (TCF7L2) gene polymorphism in patients of type 2 diabetes mellitus from Khyber Pakhtunkhwa population of Pakistan.
African health sciences - 1 Mar 2021
Hameed Taha, Khan Zahid, Imran Muhammad, Ali Saif, Albegali Abdullah Abdo, Ullah Muhammad Ikram, Ejaz Hasan
Abstract excerpt
BACKGROUND: Type 2 diabetes mellitus (T2DM) is the most prevalent component of metabolic syndrome. Environmental factors and various complex genes like transcription factor 7-like 2 (TCF7L2) gene have involved in the disease development. OBJECTIVE: To determine TCF7L2 genetic association (rs7903146C/T and rs12255372G/T) in T2DM patients of Khyber Pakhtunkhwa population of Pakistan. SUBJECTS AND METHODS: This...
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