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Article

Mapping Quantitative Trait Loci Underlying Function-Valued Traits Using Functional Principal Component Analysis and Multi-Trait Mapping.

G3 (Bethesda, Md.) - 3 Nov 2015

Kwak Il-Youp, Moore Candace R, Spalding Edgar P, Broman Karl W

Abstract excerpt

We previously proposed a simple regression-based method to map quantitative trait loci underlying function-valued phenotypes. In order to better handle the case of noisy phenotype measurements and accommodate the correlation structure among time points, we propose an alternative approach that maintains much of the simplicity and speed of the regression-based method. We overcome noisy measurements by replacing the...

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Identifiers

PMID: 26530421
DOI: 10.1534/g3.115.024133
PMCID: PMC4704727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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