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Article

The "tail" of Connexin43: An unexpected journey from alternative translation to trafficking.

Biochimica et biophysica acta - 1 Jul 2016

Basheer Wassim, Shaw Robin

Abstract excerpt

With each heartbeat, Connexin43 (Cx43) cell-cell communication gap junctions are needed to rapidly spread and coordinate excitation signals for an effective heart contraction. The correct formation and delivery of channels to their respective membrane subdomain is referred to as protein trafficking. Altered Cx43 trafficking is a dangerous complication of diseased myocardium which contributes to the arrhythmias of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26526689
DOI: 10.1016/j.bbamcr.2015.10.015
PMCID: PMC4867296

Genes

GJA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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